Festive food puts more strain on your gut than you might think — discover 5 practical steps to restore balance and lightness to your gut microbiota in the New Year

Why do festive meals put such a strain on our gut and microbiome?

The festive season is a time when we momentarily forget about eating light. The table is laden with dumplings, cabbage with mushrooms, poppy seed cake, cheesecake, fried fish, kutia and borscht with dumplings. These dishes are steeped in tradition, flavour and family memories — but for our digestive system, they’re a real marathon. Although they are delicious, they are not the easiest on the gut and the microbiota, which reacts to any excess, combinations of ingredients or sudden changes in eating patterns.

Over the two days of the festive season, we eat more, more frequently and heavier meals than we do on a daily basis. We combine fermentable foods with fat, sugar and alcohol, and on top of that, we eat larger portions than our digestive system is used to. The body has to cope with a strain it doesn’t experience throughout the rest of the year.

As a result, the typical signs of digestive overload begin to appear: bloating, a feeling of fullness, slower digestion, a drop in energy, or a ‘Christmas belly’. This is no coincidence. Every ingredient in the Christmas Eve and Christmas feasts affects the gut in a different way — from excessive fermentation, through a slowing of peristalsis, to a change in the composition of gut bacteria.

To understand why we feel the way we do after the festive season, it’s worth taking a closer look: at our gut and the microbiota that regulates our metabolism, immune system and well-being.

 What exactly happens in the gut after a festive meal?

When we tuck into a traditional twelve-course meal, our gut is working at full capacity. Every ingredient in this feast — however tasty — has its own metabolic and microbiological consequences. Here are the key processes that are triggered after a festive meal:

1. Cabbage and mushrooms cause intense fermentation

Both foods are difficult to digest and very high in insoluble fibre. This type of fibre does not dissolve in water — it passes through the intestines almost entirely intact, strongly stimulating bacterial fermentation.

Effects:
• increased gas production,
• bloating and a feeling of fullness,
• slowed bowel movements.

That’s why we feel so sluggish after eating bigos or cabbage with mushrooms. The discomfort is also made worse by gas and bloating.

2. Poppy seeds, flour and sugar put a strain on the digestive system

Poppy seed cake, kutia, poppy seed dumplings, poppy seed noodles — poppy seeds are high in fat, high in calories and rich in fibre, which ‘swells’ in the digestive tract.

When combined with sugar and flour:

• slows down the emptying of the stomach,
• puts a heavy strain on the pancreas and liver,
• leads to a feeling of fullness that lasts for hours,
• quickly raises blood glucose levels.

Furthermore, sugar promotes the growth of opportunistic bacteria and yeast, which can disrupt the gut microbiota and exacerbate inflammation. 

3. Fried foods put a strain on the pancreas and intestines

Fried carp, battered fish or cabbage croquettes are harder to digest than baked or boiled dishes.

Fat:
• slows down gastric emptying,
• hinders the action of enzymes,
• increases the feeling of heaviness.

When fat is combined with flour, it creates a particularly challenging ‘digestive mix’.

4. A mix of flavours and large portions disrupt the gut microbiota

Research shows that a sudden change in diet (high in fat, sugar and alcohol, larger portions, and no breaks between meals) can, within a few days:

• reduce the number of ‘protective’ bacteria,
• increase the proportion of pro-inflammatory bacteria.

This means that those 2–3 days of overindulgence over the festive season really do alter the gut microbiota, though fortunately this is often reversible.

Symptoms typically appear within 24–48 hours:
• bloating,
• abdominal pain,
• difficulty passing stools,
• brain fog,
• low energy.

5. Alcohol weakens the intestinal barrier and promotes inflammation

Even an occasional glass of wine or prosecco increases intestinal permeability, which can lead to what is known as ‘leaky gut syndrome’

This is because alcohol:
• damages the cells lining the intestine,
• disrupts the balance of the gut microbiota,
• exacerbates inflammation,
• puts a strain on the liver, which is responsible for detoxification.

That’s why we feel bloated and tired after the holidays — our bodies haven’t been resting, but have been struggling to maintain balance.

Why is it a good idea to ‘reset your gut’ straight after the holidays?

Because the microbiota is like a garden:
if you leave it to its own devices after a storm (i.e. after all that festive food), it will take longer to recover and may not fully recover.

However, if you give it fuel (prebiotics) and tools (probiotics), it recovers more quickly and effectively.

This is particularly important after the festive season because:
• there is more gas in the gut,
• the intestinal barrier is weakened,
• SCFA levels drop,
• the microbiota is dominated by ‘sugar-loving’ bacteria,
• immunity is temporarily reduced.

That’s exactly why the NEW YEAR is the best time to start with your gut.

5 TIPS FOR RESETTING YOUR GUT AFTER THE HOLIDAYS

(a simple plan that anyone can put into practice straight away)

After a day or two of rest, your gut is ready for a gentle but effective reset. This isn’t about fasting or radical diets — it’s simply about supporting your gut microbiota, which regulates digestion, energy levels, immunity and metabolism.

Here are five steps that deliver the quickest and most noticeable results:

1. Eat easily digestible, warming meals

After the festive season, your gut needs a break. It’s not about eating less — it’s about eating sensibly.

The best options are:
• vegetable soups (root vegetables, courgettes, carrots, pumpkin),
• boiled rice or millet,
• boiled or roasted vegetables,
• eggs, lightly cooked salmon, turkey, tofu,
• baked apple with cinnamon.Why it works:
It calms bowel movements, reduces fermentation and eases the metabolic burden.

2. Include natural probiotics and those found in supplements

After the holidays, your gut microbiota needs an extra boost of good bacteria.

Natural sources:
• sauerkraut,
• pickled gherkins,
• kimchi,
• kefir / yoghurt (if tolerated).

Unfortunately, the products mentioned above may cause problems for people with histamine intolerance. Probiotic supplements such as MegaSporeBiotic™ – which are stable, effective and resistant to stomach acid and bile – offer valuable support both for those who can consume probiotic-rich foods and for those who need to limit their intake.

Why it works:
Probiotics help increase the diversity of the gut microbiota, modulate the gut environment to benefit our good bacteria, boost immunity and aid digestion.

3. Fibre after the festive season – a gentle reset rather than another overload

Prebiotics are ‘fuel’ for good bacteria. Without them, probiotics are less effective. However, whilst fibre is essential for restoring the gut microbiota, its type and quantity are of paramount importance. Too much fibre, or the wrong kind, can exacerbate bloating, flatulence and stomach ache.

Why isn’t all fibre a good choice to start with?

After the holidays, people often:

• have a lower tolerance to highly fermentable FODMAPs,
• have digestive problems (constipation or diarrhoea),
• produce less short-chain fatty acids (SCFAs).

That is why, to begin with, it is a good idea to opt for a mild, low-fermenting and easily digestible fibre, which:

• feeds the good bacteria,
• does not cause rapid fermentation,
• promotes regular bowel movements.

The best ‘safe’ prebiotic products for after the holidays

🥕 Low-fermenting (easily digestible) vegetables

• carrots (boiled or roasted),
• courgette,
• pumpkin,
• aubergine,
• cucumber (peeled if you have a sensitive stomach),
• lettuce, lamb's lettuce, rocket.

👉 They contain soluble fibre, which is gentle on the gut and does not cause sudden flatulence.

🍚 Resistant starch (in small portions)

• cooked and cooled rice,
• boiled and cooled potatoes,
• oatmeal (preferably rolled oats, well cooked).

👉 Resistant starch is a prebiotic, but it ferments more slowly than, for example, inulin – it promotes the production of butyrate without causing an ‘intestinal revolution’.

🍌 Low-fermentation fruit

• an unripe banana,
• blueberries,
• kiwi,
• strawberries.

👉 They provide fibre and polyphenols, which support gut health and are also easier to digest after a period of overeating.

🌰 Seeds – but in an ‘intestinal’ form

• flaxseed (freshly ground, 1–2 teaspoons),
• chia seeds (soaked).

👉 They have a regulating effect – they help with both constipation and loose stools, without causing excessive fermentation.

🌿 MegaPre™ – a precise and well-tolerated prebiotic in the form of a dietary supplement

When taking a prebiotic supplement, remember to start with a small dose and increase it gradually. Also, make sure you stay well hydrated!

👉 Why it works:
Prebiotics boost the production of SCFAs — short-chain fatty acids responsible for:
✔ metabolism and energy expenditure,
✔ regulating satiety and blood glucose levels,
✔ maintaining the integrity of the intestinal barrier,
✔ reducing inflammation.

4. Cut down on: alcohol, sugar and heavy fried foods

Festive foods can be hard on the digestive system. By giving your system a short break, you’ll feel lighter again sooner.

The biggest strain on the gut:
• alcohol — increases intestinal permeability,
• sugar — feeds bacteria that are harmful to the gut microbiota,
• fried foods — slow down gastric emptying and put a strain on the liver and pancreas,
• high-lactose dairy products — increase fermentation.

👉 Why it works:
It reduces inflammation, relieves strain on the intestines, liver, stomach and pancreas, and aids in the self-repair of the intestines.

5. Hydration + light exercise = a boost for your gut

After the holidays, your bowels need some exercise, but nothing too strenuous — a 20–30-minute walk will do.

Plus plenty of fluids:
• water with lemon,
• infusions of mint, chamomile, lemon balm and fennel.

👉Why it works:
Water and exercise improve bowel motility, help to ‘get the bowels moving’ and help you pass wind more quickly.

How can you support this process with supplements?

Below are the most effective combinations, perfectly tailored to what happens in your gut after the festive season.

1. MegaPre™ + MegaSporeBiotic™ — a duo that restores the microbiota

The best combination if you want to reduce bloating and feel light again.

👉 Why it works:

• MegaPre™ increases SCFA production → improved metabolism, improved peristalsis.
• MegaSporeBiotic™ reduces dysbiosis and supports beneficial bacteria → stabilising gut health and boosting immunity.

Who it’s for: anyone feeling the effects of the festive season.

2. RestorFlora PD™ + MegaSporeBiotic™ – rapid relief and stabilisation

The perfect remedy for those suffering from diarrhoea after consuming alcohol, sweets, cabbage, bigos or fried fish.

👉Why it works:

• RestorFlora PD™ – provides rapid relief from discomfort and diarrhoea,
• MegaSporeBiotic™ – continuation of probiotic therapy following RestorFlora PD™

Who it’s for: when your gut is clearly ‘protesting’.

3. MegaSporeBiotic™ — a daily foundation for the New Year

Stable Bacillus strains restore the microbiota, support the immune system and regulate intestinal transit.

Who it’s for: anyone who wants to start the year from scratch — starting with their gut.

4. HU58™ — for people with histamine intolerance or SIBO

The festive menu is usually high in histamine and can exacerbate SIBO symptoms.

👉A strain for special tasks – B. Subtilis HU58™ – works where other probiotics may exacerbate symptoms. Safe and recommended for people with histamine intolerance and SIBO. It produces natural ‘antibiotics’ that reduce the population of harmful bacteria in the large intestine, including bacteria that produce histamine.

Who it’s for: anyone for whom conventional probiotics make symptoms worse

We invite you to read our series of articles on the microbiota and prebiotics (Part 5)

MegaPre™: a precisely targeted prebiotic

Prebiotic products, such as MegaPre, address a very real problem: most of us do not consume enough prebiotic fibre on a daily basis. The modern diet is low in natural sources of prebiotics, leaving the gut microbiota literally ‘starved’.

A product like this:

• provides concentrated, carefully selected ingredients with prebiotic properties,
• promotes the growth of bacteria essential for the production of SCFAs (including butyrate),
• can be taken on its own (as ‘fuel’ for the gut) or in combination with a probiotic,
• helps people who genuinely want to look after their gut microbiota but are unable to stick to an ‘ideal diet’ every day.
  

MegaPre can therefore be incorporated into your daily pro-microbiome routine – alongside diet, sleep and exercise.

How MegaPre™ works – key bacterial groups

The power of MegaPre™ lies in four patented ingredients whose effectiveness has been clinically proven:

Ingredient	Mechanism of action
Bimuno® (B-GOS) – galacto-oligosaccharides	It increases the number of Bifidobacterium by more than 60% and reduces levels of pro-inflammatory cytokines.
PreticX® (XOS) – xylo-oligosaccharides	It increases the levels of Bifidobacterium adolescentis and A. muciniphila, and improves glucose metabolism and insulin sensitivity.
Actazin® – green kiwi extract	A natural source of polyphenols and fibre; it stimulates bowel movements and the growth of Lactobacillus and Bifidobacterium.
Livaux® – yellow kiwi extract	A proven increase in Faecalibacterium prausnitzii levels of up to 100% within 4 weeks.

Unlike traditional dietary fibres, this combination of oligosaccharides acts biologically rather than mechanically – by stimulating beneficial bacteria and their metabolites, such as butyrate, which is crucial for the intestinal barrier and communication within the gut-brain axis.

The effects of MegaPre™:

• a 100% increase in the abundance of Faecalibacterium prausnitzii over 4 weeks,
• an 8,000% increase in the population of Akkermansia muciniphila in 5 weeks (!),
• an 80–140% increase in butyrate production (when used in combination with MegaSporeBiotic™),
• an increase in the Bifidobacteria population,
• In addition, an increase in the abundance of Prevotella and Lactobacillus was observed, accompanied by a decrease in Enterobacteria, Pseudomonas, Burkholderia, Desulfovibrio,
• an increase in SCFA production (mainly butyrate).
  

What does this mean?

• Improving the integrity of the intestinal barrier
• Modulation of the immune response and reduction of inflammation
• Effects on lipid and glucose metabolism
• Improved bowel motility
• Optimising digestion and nutrient absorption

Or even simpler?

• Better immunity,
• Greater control over body weight (the gut microbiota influences feelings of fullness and hunger),
• More regular bowel movements and improved stool consistency,
• Improved gut health (less pain, less constipation, less gas and bloating),
• A stronger immune system and improved well-being!

Why is MegaPre™ so effective?

✔️ MegaPre’s selective action
on specific groups of bacteria means it is not a “blanket, indiscriminate fibre”, but a targeted prebiotic that strengthens strictly defined bacterial populations with a beneficial metabolic profile.

✔️ Synergy with probiotics
Adding MegaPre™ to a probiotic:

• increases the survival rate of strains by up to several times,
• accelerates their proliferation and metabolic activation,
• stabilises colonisation,
• increases SCFA production,
• reduces the overgrowth of opportunistic microorganisms.

✔️ Restoring key functions of the microbiota following antibiotic treatment
Research into prebiotics of this type has shown:

• a quicker recovery of microbial diversity,
• an increase in the population of butyrate-producing bacteria (important in IBD and IBS-C),
• regeneration of the intestinal mucosa.

MegaPre™ – clinical application

✔️ After taking antibiotics and other medicines that adversely affect the microbiome.
Support to help speed up the recovery of the microbiota.

✔️ Constipation, bloating
: Improves stool consistency, regulates bowel movements, reduces discomfort and regulates bowel movement patterns.

✔️ Inflammatory bowel disease (IBD in remission)
Supporting butyrate production = supporting clinical remission (as part of treatment, not as a substitute for it).

✔️ Metabolic
disorders: Effects on blood glucose levels and lipid metabolism via SCFAs.

✔️ Immunity:
Increased Treg activity, reduced Th2 response, improved regulation of inflammation.

FAQ – customers’ most frequently asked questions about MegaPre™

How does MegaPre™ differ from ordinary fibre?

MegaPre™ is a targeted prebiotic, meaning it does not act on ‘the entire gut microbiota’ but specifically on certain beneficial groups of bacteria in the gut. Ordinary fibre mainly performs mechanical functions: it increases stool bulk and supports peristalsis. MegaPre™ has been designed to strengthen the bacteria responsible for butyrate production, intestinal barrier repair and maintaining microbiota balance – it acts more as a therapeutic tool than as ‘general fibre’. 

What further sets it apart is the use of patented, clinically tested oligosaccharides with proven efficacy (Bimuno®, PreticX®) and two types of kiwi powder:

Actazin® is a powdered green kiwi (the ‘green kiwifruit’ variety), processed in such a way as to preserve the fibre, enzymes (including actinidin), cell wall polysaccharides and other bioactive components. 

Livaux® is a powdered ‘gold kiwi’, processed in the same way, rich in fibre (soluble — pectin, and insoluble — hemicellulose/cellulose), polyphenols, vitamins and other bioactive compounds. 

These are ‘low-fermentation’ prebiotic ingredients with a relatively mild effect. They can support the gut microbiome, SCFA production, bowel motility and gut comfort, potentially without the risk of excessive gas or bloating, which can be a problem with traditional prebiotics.

Can MegaPre cause bloating when you first start taking it?

Yes, this is a normal adaptive response. Prebiotics ferment in the large intestine, and fermentation naturally produces gas. In people with a ‘hungry’ microbiota, the initial bloating may be more severe, but it usually subsides after a few days.

How to reduce discomfort:

• start with half the dose,
• drink more water,
• increase the dose gradually,
• use it regularly, rather than just now and then.

How long do you need to use MegaPre™ before you see results?

The effects depend on the objective: regularity of bowel movements may become apparent after just 5–14 days; improved gut comfort and reduced bloating after 2–4 weeks; and restoration of the gut microbiota following a course of antibiotics after 4–12 weeks.

Can MegaPre™ be combined with any probiotic?

 Yes, MegaPre is compatible with most probiotics. Its role is to provide ‘fuel’ for the bacteria we already have in our bodies and those we take in capsule form. This helps the probiotics survive better and work more effectively.

When is the best time to take MegaPre™?

 At any time of day, but:

• on an empty stomach or with a meal,
• washed down with a sufficient amount of water,
• Use it every day at the same time.

The capsules can be opened and the contents sprinkled into a drink or yoghurt – this makes taking the supplement particularly easy for people who have difficulty swallowing and for young children.

Read now or save for later:

Part 1: Why is the gut microbiota so important?: https://novolabs.pl/artykul/dlaczego-mikrobiota-jelitowa-ma-takie-znaczenie/

Part 2: How probiotics and prebiotics work: https://novolabs.pl/artykul/jak-dzialaja-probiotyki-i-prebiotyki/

Part 3: Why does combining a prebiotic and a probiotic (a synbiotic) produce the best results?: https://novolabs.pl/artykul/dlaczego-synbiotyk-dziala-najskuteczniej-i-dla-kogo/

Part 4: Frequently asked questions about prebiotics and probiotics: https://novolabs.pl/artykul/najczesciej-zadawane-pytania-o-prebiotyki-i-probiotyki/

Part 5: MegaPre™: a precisely targeted prebiotic https://novolabs.pl/artykul/megapre-precyzyjnie-ukierunkowany-prebiotyk/

Part 6: For experts: MegaPre™ in clinical practice https://novolabs.pl/artykul/dla-ekspertow-megapre-w-praktyce-klinicznej/

Planning a holiday? Look after your gut! Find out how to avoid traveller’s diarrhoea and discover a probiotic that’s worth keeping with you at all times – RestorFlora™ PD.

Traveller’s diarrhoea – what exactly is it?

For many of us, holidays are a time for relaxation, sunshine and new flavours. Unfortunately, they can just as often pose a challenge for our digestive system. One of the most common problems that can ruin even the best-planned holiday is traveller’s diarrhoea.

It is an acute gastrointestinal infection that usually affects people travelling to countries with lower standards of hygiene. Symptoms include frequent, loose stools, abdominal pain, nausea and sometimes a fever. Most cases are mild, but it can effectively ground a traveller for a few days – and put a stop to their holiday plans.

Where is the risk greatest?

The risk is not the same everywhere. According to WHO data, traveller’s diarrhoea most commonly affects people visiting:

• Southeast Asia (India, Thailand, Indonesia),
• Africa (particularly North Africa and Sub-Saharan Africa),
• Latin America (Mexico, Peru, Brazil),
• and the Middle East.

The risk is moderate in Eastern Europe and the Balkans, and lowest in Western Europe, the USA, Canada, Australia and Japan.

What causes traveller’s diarrhoea?

The main cause is bacteria – they account for as many as 80% of cases. The most common culprit is enterotoxigenic Escherichia coli (ETEC), but Shigella, Salmonella and Campylobacter are also frequent causes, as are viruses (e.g. noroviruses) and parasites (e.g. Giardia lamblia).

Infection occurs through the consumption of contaminated water, ice, raw fruit and vegetables, undercooked meat or unpasteurised milk. Sometimes, just a single sip of local water or an ice cube in a drink is enough.

How can you protect yourself against diarrhoea whilst travelling?

Prevention is key. Good hygiene, taking care when eating and drinking, and boosting gut immunity can significantly reduce the risk.

Rules worth following:

• Drink only bottled or boiled water – even when brushing your teeth.
• Avoid ice in your drinks (it is often made from tap water).
• Eat only well-cooked, fresh meals – preferably served hot.
• Peel your own fruit and vegetables, or eat those that can be blanched.
• Wash your hands before meals or use hand sanitiser.
• Avoid raw seafood, unpasteurised cheese and street food of unknown origin.

It’s also a good idea to boost your gut flora with a suitable probiotic before you travel – and take some with you just in case.

RestorFlora™ PD – a modern probiotic that works on multiple levels

RestorFlora™ PD is a four-strain probiotic, specially formulated for:

• the prevention and treatment of diarrhoea of various causes (including traveller’s diarrhoea),
• supporting gut flora after a course of antibiotics,
• improving immunity and digestive comfort.

It is one of the few probiotics that can be safely taken alongside a course of antibiotics – all the strains are naturally resistant to them. What’s more, the product does not need to be refrigerated, making it ideal for travelling.

How does RestorFlora™ PD work? Discover its probiotic strains

🦠 Saccharomyces boulardii CNCM I-1079 A
probiotic yeast with powerful protective properties:

• binds toxins produced by pathogens (C. difficile, E. coli),
• helps to restore the intestinal lining,
• shortens the duration of diarrhoea and reduces the risk of recurrence,
• has anti-inflammatory properties.

🦠 Bacillus subtilis HU58™ A
highly resilient spore-forming bacterium:

• produces digestive enzymes (amylases, proteases),
• supports digestion and the balance of the microbiome,
• is effective against pathogens,
• stimulates the production of SCFAs (short-chain fatty acids that are important for gut health).

🦠 Bacillus clausii SC-109
A strain that has been used for years to treat diarrhoea:

• resistant to many antibiotics,
• supports the immune system and gut flora,
• regulates bowel function.

🦠 Bacillus coagulans SC-208
produces lactic acid and aids digestion:

• reduces bloating and stomach ache,
• improves lactose digestion (ideal for those with lactose intolerance),
• promotes the growth of beneficial gut bacteria.

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Who should use RestorFlora™ PD?

This product is suitable for people who:

• those planning to travel to countries with an increased risk of traveller’s diarrhoea,
• during or after a course of antibiotics,
• people suffering from recurrent diarrhoea, IBD or dysbiosis,
• with food intolerances and irritable bowel syndrome,
• who wish to take preventive measures and support gut health.

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Why should you take him on holiday?

• No need to keep it in the fridge – perfect for your suitcase or travel first-aid kit.
• Antibiotic resistance – can be used alongside other medicines.
• It works quickly – it shortens the duration of diarrhoea and helps prevent it from returning.
• Multi-level support – it has enzymatic, immunomodulatory and antimicrobial effects.

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Summary

Traveller’s diarrhoea is a problem that can be avoided – prevention, care in choosing what to eat and drink, and proper support for the gut microbiota are key.
RestorFlora™ PD is a modern, multi-strain probiotic that provides effective protection both whilst travelling and during antibiotic treatment. Thanks to its resistance to antibiotics, the fact that it does not require refrigeration, and its broad spectrum of action, it is an indispensable aid for the gut – whenever you need it.

What is coeliac disease?

Coeliac disease, also known as gluten-induced enteropathy, is a chronic autoimmune condition that affects the body’s ability to digest gluten. Gluten is a protein found in, amongst other things, wheat, rye and barley – grains that are commonly used in many food products. In people with coeliac disease, consumption of this protein triggers a reaction from the immune system and the destruction of the intestinal villi, which are crucial for the absorption of nutrients. This leads to numerous deficiencies and health problems.

What are the symptoms of coeliac disease?

The classic symptoms of coeliac disease (mainly seen in children) include:

• oily or watery diarrhoea,
• weight loss, losing weight, symptoms of malnutrition,
• stomach ache,
• fatigue, lethargy,
• developmental disorders, mood swings, short stature, lack of muscle mass, loss of appetite, bloated stomach.

Non-classical, extraintestinal symptoms include:

• anaemia caused by a deficiency of iron, vitamin B12 and folic acid,
• high cholesterol, 
• elevated levels of transaminases (so-called liver function tests), 
• pancreatic diseases,
• mouth ulcers and ulcerative stomatitis, enamel hypoplasia,
• chronic fatigue syndrome, drowsiness,
• obstructive sleep apnoea, nosebleeds, sensorineural hearing loss
• neurological disorders (peripheral neuropathy – sensory disturbances and numbness in the limbs, coeliac ataxia – impaired motor coordination, dizziness, epilepsy, migraine headaches, so-called ‘brain fog’ – impaired cognitive function),
• depression, anxiety, eating disorders, psychosis, ADHD,
• early-onset osteoporosis, osteopenia and osteomalacia, frequent fractures,
• bone, joint and muscle pain, arthritis,
• kidney disease, IgA nephropathy,
• skin conditions: Dühring’s disease – the cutaneous form of coeliac disease, psoriasis, urticaria, atopic dermatitis,
• miscarriages, fertility problems, delayed puberty and early menopause in women,
• coexisting autoimmune conditions (type 1 diabetes, Hashimoto’s disease, joint, liver and skin conditions, etc.),
• deficiencies in vitamins and minerals (found in almost 90% of newly diagnosed patients).

How is coeliac disease diagnosed?

SEROLOGICAL TESTS

Diagnosing coeliac disease can be complex. Several methods are used for this purpose. Serological tests, i.e. blood serum tests, are the first line of investigation:

• total IgA antibody levels,
• antibodies against tissue transglutaminase (tTG), 
• anti-endomysial antibodies (EMA),
• antibodies against deamidated gliadin (DPG).

We do not need to carry out all these tests straight away. According to the 2020 guidelines from ESPGHAN (the European Society for Paediatric Gastroenterology, Hepatology and Nutrition), the first step should be to measure total IgA antibody levels and to test for antibodies against tissue transglutaminase.

If IgA levels are normal and there are no IgA-class antibodies against tissue transglutaminase, we can effectively rule out coeliac disease with 99% certainty. However, there are very rare cases where symptoms are present and further diagnostic tests are required.

SMALL INTESTINE BIOPSY

It should be emphasised that the absence of specific antibodies does not always rule out coeliac disease. According to the latest research, between 6 and 22% of people with coeliac disease do not produce any antibodies at all. Therefore, a small intestine biopsy is necessary for a definitive diagnosis. It is performed on patients with positive serological test results and can be used to determine whether the intestinal villi have been damaged in a manner typical of coeliac disease. The Marsh scale is used to assess the condition of the intestine:

An endoscopic examination alone is not sufficient to make a diagnosis, as damage to the villi can also occur as a result of other conditions.

EXAMINATION OF THE GASTROINTESTINAL TRACT USING A CROSBY CAPSULE

A Crosby capsule examination of the intestine, also known as capsule endoscopy of the small intestine, involves swallowing or inserting via a probe a small capsule equipped with a camera and a light source, which travels through the digestive tract, recording images of the inner surface of the intestine and taking samples. This method does not require sedation.

GENETIC TESTING

The sample used for the test is blood taken from the patient’s vein. The test is designed to detect the DQ2 and DQ8 genes. Genetic testing has clear advantages:

the test result is valid for life;

effectively rules out coeliac disease, saving the patient time and money on further tests for gluten intolerance, including regular repeat antibody tests;

the examination is painless and non-invasive;

You can also take this coeliac disease test whilst following a gluten-free diet.

It should be noted that a person who tests positive does not necessarily develop coeliac disease. The test helps to distinguish the condition from other gluten-related disorders.

Other gluten-related disorders

In addition to coeliac disease, there are other reasons for following a gluten-free diet. The most common include NCGS (non-coeliac gluten sensitivity) and wheat allergy. These reactions can occur through various mechanisms. 

Like coeliac disease, NCGS is a systemic condition whose symptoms are not limited to the gut. Conditions and symptoms linked by researchers to NCGS include: skin conditions, gluten-induced ataxia, gluten-induced neuropathy, encephalopathy, psychiatric disorders (e.g. depression), rheumatic diseases, fibromyalgia, and nutrient deficiencies caused by malabsorption and their consequences. Autoimmune diseases such as Hashimoto’s disease, psoriasis, type 1 diabetes and ankylosing spondylitis are also more common than in healthy individuals.

An allergy is an IgE-mediated reaction. It can be diagnosed using skin tests or blood tests. In the case of food hypersensitivity, the only reliable method is an elimination diet and observation of symptoms. It should be emphasised that the food intolerance tests currently popular on the market, which measure IgG and IgA antibodies, have limited diagnostic value, as positive results do not necessarily correspond to symptoms.

Who is at risk of developing coeliac disease?

It was once believed that only children were affected, but this view was based solely on the classic form of coeliac disease associated with malabsorption, which manifested itself in young children following the introduction of gluten into their diet. They experienced classic symptoms such as: chronic diarrhoea with very characteristic fatty stools, abdominal pain, abdominal distension, stunted growth, weight loss, anaemia and lethargy. 

We now know that anyone can develop the condition at any age, and diagnosis is made more difficult by the fact that coeliac disease can occur without these classic symptoms. What’s more, this non-classic form of coeliac disease is much more common. 

In adults with coeliac disease, the classic symptoms may differ from those seen in children. Weight loss is often not observed; instead, patients may be overweight or obese. Coeliac disease may co-occur with other autoimmune diseases and diabetes. Instead of chronic diarrhoea, patients may experience it only sporadically or suffer from bloating. Therefore, it is not possible to make a definitive diagnosis based solely on the symptoms reported by the patient. It is also very common for only the symptoms or conditions caused by coeliac disease to be treated, which does not yield long-term results. 

Given the wide variety of symptoms associated with coeliac disease, doctors from almost every specialism should take a closer interest in it: gastroenterologists, allergists, endocrinologists, gynaecologists, haematologists, rheumatologists, psychiatrists, neurologists, dermatologists, etc.

Can you develop coeliac disease at any age?

Yes, coeliac disease can occur at any age, in children, teenagers and adults alike. In some cases, symptoms may appear in early childhood following the introduction of gluten into an infant’s diet. In some people, coeliac disease may develop later in life, even in older adults.

How is coeliac disease treated?

The only effective treatment for coeliac disease is to eliminate gluten from the diet. Once diagnosed, patients must follow a gluten-free diet for the rest of their lives. Avoiding foods containing wheat, rye, barley and oats, and opting for safe food alternatives, will help reduce inflammation in the intestines and alleviate symptoms. People with coeliac disease should be under the care not only of doctors but also of a dietitian, who will teach them a new way of eating, ensuring that the gluten-free diet does not lead to nutritional deficiencies.

What should you avoid eating if you have coeliac disease?

In short – anything containing gluten, which is a protein found in cereals such as wheat, rye and barley. Oats, unless they are labelled with the crossed-out ear symbol (the gluten-free label), should also be considered a cereal containing gluten. Gluten-free grains include, amongst others: rice, maize, buckwheat, millet, amaranth, quinoa, teff and sorghum; however, to be 100% certain, all products should be certified. 

Supplementation is an important way to enhance your diet, and you should focus on:

• reducing inflammation,
• intestinal regeneration,
• to address nutritional deficiencies.

This is where our TGR – Comprehensive Intestinal Regeneration System – comes into its own!

Summary

In summary, coeliac disease is a digestive disorder caused by an intolerance to gluten. It can affect many aspects of health, so it is important to be aware of the symptoms and to consult a doctor if you suspect you may have it. Early diagnosis and the elimination of gluten from the diet are crucial for maintaining the health and quality of life of people with coeliac disease.

The process of intestinal regeneration begins with probiotic therapy using one of two preparations: MegaSporeBiotic™ or MegaSporeBiotic Plus™ (enriched with antioxidants).

STEP 1 RECONDITION – restoring balance

MegaSporeBiotic™ is a probiotic containing 100% viable bacterial endospores with a broad spectrum of activity and clinically proven efficacy. It reduces intestinal dysbiosis by up to 60% in just 30 days. It modifies the gut environment by supporting microbial diversity, promoting the growth of key commensal bacteria, limiting populations of potentially pathogenic bacteria, and modulating the immune response.

The two-phase life cycle of Bacillus spores enables them to remain dormant in the harsh conditions of the human stomach and to become active in the more favourable intestinal environment, where they begin a temporary colonisation and the process of intestinal repair. 

Published scientific studies show that the spores contained in MegaSporeBiotic™reduce the amount of LPS endotoxin circulating in the blood, which causes chronic low-grade inflammation linked to many metabolic and cardiovascular diseases, as well as neurodegenerative conditions and depression.

Unlike conventional probiotics, MegaSporeBiotic™ is highly resistant to temperature fluctuations and does not need to be kept in the fridge.

STEP 2: REINFORCE – reinforcing positive changes

After a month of taking the probiotic, we introduce the prebiotic.

MegaPre™ is the second step in the TGR programme and the first precision prebiotic on the market consisting of clinically tested non-digestible oligosaccharides. It selectively feeds beneficial bacteria such as Akkermansia muciniphila, Faecalibacterium prausnitzii and Bifidobacteria, whose metabolites (including short-chain fatty acids) support our health.

MegaPre™ ENHANCES the beneficial changes induced by MegaSporeBiotic™ to promote a robust and diverse microbiome.

MegaPre™ ENHANCES the beneficial changes induced by MegaSporeBiotic™ to promote a robust and diverse microbiome.

STEP 3: REBUILD – restoring the intestinal barrier

Next month, following on from the probiotic and prebiotic, we’ll be adding an intestinal regenerator to our daily routine.

When the protective layer of the intestinal mucosa becomes compromised, toxins and other harmful particles enter the bloodstream.

MegaMucosa™ is the first comprehensive supplement designed to support the mucous membrane, created to RESTORE a healthy intestinal barrier.

MegaMucosa contains high doses of amino acids that are essential for gut health, as well as a blend of bioflavonoids that support microbial diversity, reduce inflammation and alleviate barrier dysfunction, also known as ‘leaky gut syndrome’.